Research Articles
Unmasking Hidden Bias: How DNA Extraction Kit Batch Effects Skew Microbiome and Epigenetic Data
For researchers and drug development professionals, accurate data is paramount.
Demethylation Dynamics: The Epigenetic Key to Cellular Reprogramming and Regenerative Medicine
This article provides a comprehensive review of the pivotal role of DNA demethylation in cellular reprogramming, targeting researchers and biotech professionals.
Decoding Chromatin Evolution: Cross-Species Analysis of Histone Variant Repertoires, Functions, and Biomedical Implications
This review provides a comprehensive analysis of histone variant diversity and evolution across the tree of life, targeting researchers, scientists, and drug development professionals.
Ensuring 3D Genome Reliability: A Comprehensive Guide to Cross-Platform Validation of Hi-C, ChIA-PET, and Capture-C Data
This article provides a systematic framework for researchers, scientists, and drug development professionals to validate chromatin conformation capture (3C) data across different platforms and technologies.
Decoding the Epigenetic Clock: How ELOVL2 and FHL2 CpG Sites Predict Biological Age
This article provides a comprehensive analysis for researchers and drug development professionals on the CpG sites within the ELOVL2 and FHL2 genes, which are among the most robust biomarkers for...
Mastering CpG Site Selection: The Critical Step for Sensitive and Specific Liquid Biopsy DNA Methylation Biomarkers
This article provides a comprehensive guide for researchers and drug development professionals on the strategic selection of CpG sites for liquid biopsy methylation biomarkers.
CpG Islands and DNA Methylation Analysis: A Comprehensive Guide for Researchers in Epigenetics and Drug Development
This comprehensive guide explores the critical role of CpG islands in gene regulation through DNA methylation, a cornerstone of epigenetic research.
Decoding Tumor Evolution: A Comparative Analysis of CpG Island Methylation in Primary Tumors and Metastatic Sites
This article provides a comprehensive analysis of CpG island methylation dynamics between primary tumors and their metastatic counterparts.
CpG Island Methylation: The Molecular Gatekeeper of Gene Silencing in Development and Disease
This comprehensive review explores the critical role of CpG island (CGI) methylation in the epigenetic regulation of gene expression.
RRBS vs. WGBS vs. MeDIP: A Comprehensive Guide to CpG Density Coverage in DNA Methylation Analysis
This article provides researchers, scientists, and drug development professionals with a detailed comparison of CpG density coverage across three primary DNA methylation profiling techniques: Reduced Representation Bisulfite Sequencing (RRBS), Whole-Genome...